Kilolo is one of the four districts of the Iringa Region of Tanzania. It is bordered to the north and east by the Morogoro Region, to the south by Mufindi District and to the west by the Iringa Rural District. The district is home to the Udzungwa Mountains National Park.
According to the 2002 Tanzania National Census, the population of the Kilolo District was 205,081
As of 2015, Kilolo District is administratively divided into wards: Bomalang’ombe, Dabaga, Ibumu, Idete, Ihimbo, Ilula, Image, Irole, Kising’a, Kimala, Kitowo, Lugalo, Mahenge, Masisiwe, Mawambala, Mlafu, Mtitu, Ng’ang’ange, Ng’uruhe, Nyalumbu, Nyanzwa, Ruaha Mbuyuni, Udekwa, Uhambingeto, Ukumbi, Ukwega and Winome